IN ACUTE RENAL FAILURE PREVENTION

Beneficial
Low osmolality contrast media

Likely to be beneficial
Fluids
Single (better than multiple doses of aminoglycosides)

Unknown effectiveness
Acetylcysteine
Lipid formulations of amphotericin (better than standard formulations)

Unlikely to be beneficial
Mannitol

Likely to be ineffective or harmful
Loop diuretics
Dopamine receptor agonists
Natriuretics peptides
Adenosine antagonists (theophylline) in ARF induced by contrast media
Cacium channel blockers for early allograft dysfunction

TREATMENTS FOR ACUTE RENAL FAILURE IN CRITICALLY ILL PEOPLE

Likely to be beneficial
Biocompatible dialysis membranes (better than non-biocompatible membranes)

Unknown effectiveness
Continuous versus intermittent rnal replacement therapy
Dopamine for treating acute renal in critically ill people
Loop diuretics
Continuous versus bolus diuretics
Combined diuretics and albumin

Unlikely to be beneficial
Natriuretic peptides

Likely to be ineffective or harmful
Endothelin receptor antagonists
Antibodies against adhesion molecules
Growth factors
Noradrenaline
Antioxidants
Nutritional management

Clinical Evidence 6 issue December 2001